Omidenepag
CAS No. : 1187451-41-7
(Synonyms: UR-7276)
| Size | Price | Stock |
|---|---|---|
| 5mg | $120 | In-stock |
| 10mg | $190 | In-stock |
| 25mg | $385 | In-stock |
| 50mg | $620 | In-stock |
| 100mg | $990 | In-stock |
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| Cat. No. : | HY-17642 |
| M.Wt: | 478.52 |
| Formula: | C23H22N6O4S |
| Purity: | >98 % |
| Solubility: | DMSO : 250 mg/mL (ultrasonic) |
Omidenepag (UR-7276), a pharmacologically active form of Omidenepag Isopropyl, is a selective, non-prostanoid EP2 receptor agonist, with an EC50 of 1.1 nM. Omidenepag shows binding affinities (IC50) 10 nM for h-EP2. Omidenepag is used in research on diseases related to intraocular pressure[1][2].
In Vitro: Omidenepag (3-30 μM) significantly inhibits Carbachol (HY-B1208)-induced porcine ciliary muscle (CM) contraction[2].
Omidenepag (10-100 nM; 24 h) significantly inhibits TGF-β2-induced mRNA upregulation of αSMA, COL1A1 and FN in HTM cells[2].
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