Antihistamine-1
CAS No. : 1186430-60-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $83 | In-stock |
| 10mg | $132 | In-stock |
| 25mg | $264 | In-stock |
| 50mg | $423 | In-stock |
| 100mg | $676 | In-stock |
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| Cat. No. : | HY-100238 |
| M.Wt: | 389.47 |
| Formula: | C23H24FN5 |
| Purity: | >98 % |
| Solubility: | DMSO : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
Antihistamine-1 is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively. IC50 & Target: Ki: 6.9 nM (H1-antihistamine)[1] IC50: 5.4 μM (CYP2D6), 0.8 μM (hERG channel)[1] In Vitro: Antihistamine-1 (Compound 2) is a H1-antihistamine (Ki=6.9 nM) with acceptable blood-brain barrier penetration and also an inhibitor of CYP2D6 and hERG channel with IC50s of 5.4 and 0.8 μM, respectively[1].
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