DBPR108


CAS No. : 1186426-66-3

1186426-66-3
Price and Availability of CAS No. : 1186426-66-3
Size Price Stock
5mg $178 In-stock
10mg $238 In-stock
25mg $397 In-stock
50mg $567 In-stock
100mg $768 In-stock
200 mg Get quote
500 mg Get quote
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Cat. No. : HY-12528
M.Wt: 324.39
Formula: C16H25FN4O2
Purity: >98 %
Solubility: DMSO : ≥ 25 mg/mL
Introduction of 1186426-66-3 :

DBPR108 is a potent, selective, and orally bioavailable dipeptide-derived inhibitor of DPP4 with IC50 of 15 nM; no inhibition on DDP8 and DPP9. IC50 value: 15 nM [1] Target: DPP4 inhibitor DBPR108 is an IC50=15 nM DPP IV inhibitor displays a more than 3000-fold selectivity over DPP8 DPP9, FAP and DPP-II. TThe in vivo effects of DBPR108, including inhibition of plasma DPP-IV activity and suppression of blood glucose elevation, were also demonstrated. DBPR108 is a potent, selective, long-acting and safe DPP-IV inhibitor as a potential treatment of type 2 diabetes mellitus.

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