HL001
CAS No. : 1186371-31-2
| Size | Price | Stock |
|---|---|---|
| 5mg | $280 | In-stock |
| 10mg | $450 | In-stock |
| 25mg | $900 | In-stock |
| 50mg | $1450 | In-stock |
| 100mg | $2350 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-124072 |
| M.Wt: | 360.36 |
| Formula: | C21H16N2O4 |
| Purity: | >98 % |
| Solubility: |
HL001 is an orally active small molecule inhibitor of Cyclophilin A (CypA) and a receptor antagonist of Lysophosphatidic acid 1 (LPA1). HL001 induces cell cycle arrest and apoptosis of tumor cells by p53. HL001 stabilizes p53 by down-regulating G3BP1, inducing reactive oxygen species and DNA damage. HL001 disrupts the interaction between MDM2 and p53-72R in a CypA dependent manner. HL001 has antitumor activity. HL001 can also be used to study pulmonary fibrosis[1][2].
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