EC-70124
CAS No. : 1185908-92-2
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| Cat. No. : | HY-124067 |
| M.Wt: | 453.45 |
| Formula: | C26H19N3O5 |
| Purity: | >98 % |
| Solubility: |
EC-70124 is an orally active multikinase inhibitor targeting IKKβ and JAK2. EC-70124 blocks IkB phosphorylation and STAT3 (Tyr705) activation, suppressing NF-κB nuclear translocation and STAT3 transcriptional activity. EC-70124 reduces tumor growth and cancer stem cell (CSC) populations in prostate cancer cells and xenograft models. EC-70124 is promising for research of prostate cancer[1].
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