NVP-BVU972
CAS No. : 1185763-69-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $50 | In-stock |
| 5mg | $140 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $380 | In-stock |
| 50mg | $540 | In-stock |
| 100mg | $760 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15456 |
| M.Wt: | 340.38 |
| Formula: | C20H16N6 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
NVP-BVU972 is an selective and potent Met inhibitor, with an IC50 of 14 nM. NVP-BVU972 also exhibits good anti-proliferative activity against Met with drug-resistant mutations and inhibits phosphorylation. NVP-BVU972 can be used in study of cancer[1].
In Vitro: NVP-BVU972 (600 nM-9.6 µM; 72 h) shows good antiproliferative activity to BaF3 cells with MET mutations[1].
NVP-BVU972 (0-10 µM; 2 h) reduces TPR-MET phosphorylation in a dose-dependent manner in BaF3 TPR-MET cells[1].
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