Tesmilifene (fumarate)


CAS No. : 1185241-83-1

(Synonyms: DPPE (fumarate))

1185241-83-1
Price and Availability of CAS No. : 1185241-83-1
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5mg $85 In-stock
10mg $130 In-stock
25mg $240 In-stock
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Cat. No. : HY-101179
M.Wt: 399.48
Formula: C23H29NO5
Purity: >98 %
Solubility: DMSO : 125 mg/mL (ultrasonic)
Introduction of 1185241-83-1 :

Tesmilifene fumarate (DPPE fumarate), an H1C receptor antagonist, potentiates a wide range of cytotoxics and even to offer some protection of normal cells[1][2]. In Vitro: Tesmilifene may modulate the effects of 12(S)HETE in cancer cells, and indirectly, influence the susceptibility of cellular DNA to chemotherapy[1]. In Vivo: Tesmilifene (DPPE, 20 mg/kg (s.c.) and 20 μg (icv in 5 μL)) potentiated seizures induced by both convulsants[2].

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