Cyprodime
CAS No. : 118111-54-9
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| Cat. No. : | HY-107750 |
| M.Wt: | 355.47 |
| Formula: | C22H29NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Cyprodime is a selective µ opioid receptor (MOR) antagonist with Kis of 5.4, 244.6, and 2187 nM for µ, δ, and κ, respectively[1]. In Vivo: Cyprodime (0.003-1 mg/kg; i.v.) do not significantly change the control bladder capacity during repeated acetic acid (AA) cystometrogram (CMG) but significantly reduces tibial nerve stimulation (TNS) inhibition starting from the 0.1 mg/kg dose and completely eliminates the inhibition induced by both 2 T and 4 T TNS at doses of 0.3-1 mg/kg[2].
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