Syringin


CAS No. : 118-34-3

(Synonyms: Eleutheroside B)

118-34-3
Price and Availability of CAS No. : 118-34-3
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1g $242 In-stock
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Cat. No. : HY-N0824
M.Wt: 372.37
Formula: C17H24O9
Purity: >98 %
Solubility: DMSO : 100 mg/mL (ultrasonic)
Introduction of 118-34-3 :

Syringin (Eleutheroside B) is an active natural phenolic glycoside possessing various pharmacological activities, including anti-inflammatory, anti-irradiation, anti-osteoporosis and anticancer activities. Syringin also can be used to enhance memory, relieve fatigue, improve human cognition and protect ischemia heart against cerebrovascular damage, etc[1]. In Vitro:Syringin (15 µM; 24 h) results in a marked decrease in the expression levels of hypertrophic markers and an inrease in the levels of α-MHC[2]. In Vivo:Syringin (10-40 mg/kg; orally active, daily, 12 weeks) significantly downregulates the expression of TRAF6, NF-κB and RANKL proteins levels, upregulated the expression of osteoprotegerin (OPG), PI3K and AKT levels, and subsequently increasing the OPG/RANKL ratio and inhibiting the osteoclastogenesis, finally promoting bone formation[1].

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