1-Cinnamoyltrichilinin
CAS No. : 117869-72-4
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| Cat. No. : | HY-107298 |
| M.Wt: | 658.78 |
| Formula: | C39H46O9 |
| Purity: | >98 % |
| Solubility: |
1-Cinnamoyltrichilinin can inhibit the viability of HL-60 human leukemia cells, induce apoptosis of HL-60 cells, and increase nuclear fragmentation and fractional DNA content by activating the p38 MAPK pathway. The anti-cancer properties of 1-Cinnamoyltrichilinin are only effective against HL-60 cells, not in other human cancer cell lines, such as epidermoid carcinoma (A431), lung epithelial carcinoma (A549), and mammary gland adenocarcinoma (MCF7), at a 20 µM concentration, which is otherwise not toxic to a normal cell line (RAW 264.7). 1-Cinnamoyltrichilinin can be used in the research of leukemia[1].
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