cis-α-(Carboxycyclopropyl)glycine
CAS No. : 117857-95-1
(Synonyms: L-CCG III)
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| Cat. No. : | HY-100838 |
| M.Wt: | 159.14 |
| Formula: | C6H9NO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
cis-α-(Carboxycyclopropyl)glycine (L-CCG III) is a potent, competitive glutamate uptake inhibitor. cis-α-(Carboxycyclopropyl)glycine is a substrate of glutamate transporters (GluT) (EC50: 13 μM, 2 μM for EAAT 1 and EAAT 2, respectively). cis-α-(Carboxycyclopropyl)glycine inhibits a Na+-dependent high-affinity L-glutamate uptake in glial plasmalemmal vesicles (GPV) and synaptosomes[1][2]. IC50 & Target:Glutamate transporters (GluT)[1]
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