L-CCG-I


CAS No. : 117857-93-9

117857-93-9
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Cat. No. : HY-100838A
M.Wt: 159.14
Formula: C6H9NO4
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 117857-93-9 :

L-CCG-I is an extended isomer of conformationally restricted glutamate analog. L-CCG-I also is a potent agonist for mGluR2 with an EC50 value of 0.3 nM. L-CCG-I can be used for the research of mGluR family[1]. IC50 & Target:EC50: 0.3 nM (mGluR2)[1] In Vitro:L-CCG-I has activity for mGluR2 with an EC50 value of 0.3 nM[1].
LCCG-I effectively stimulated phosphatidylinositol hydrolysis in mGluR1-expressing cells[1].
L-CCG-I can inhibit the forskolin-stimulated adenosine 3':5'-cyclic monophosphate (cyclic AMP) accumulation in mGluR2-expressing cells[1].
L-CCG-I evoked an inhibition of the forskolin-stimulated cyclic AMP production characteristic of mGluR4[1].

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