CGH2466 (dihydrochloride)


CAS No. : 1177618-54-0

1177618-54-0
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Cat. No. : HY-103167
M.Wt: 395.13
Formula: C14H11Cl4N3S
Purity: >98 %
Solubility:
Introduction of 1177618-54-0 :

CGH 2466 dihydrochloride is an orally active adenosine A1, A2B and A3 receptor antagonist with the IC50 values of 19 nM, 21 nM, and 80 nM respectively. CGH 2466 dihydrochloride inhibits p38 MAPK (IC50 = 187~ 400 nM) and phosphodiesterase type 4D (IC50 = 22 nM). CGH 2466 dihydrochloride displays potent anti-inflammatory effects both in vitro and in vivo, and can be used for research on asthma and chronic obstructive pulmonary disease (COPD)[1].

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