RP-60503
CAS No. : 117705-18-7
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| Cat. No. : | HY-101643 |
| M.Wt: | 438.86 |
| Formula: | C22H19ClN4O4 |
| Purity: | >98 % |
| Solubility: |
RP-60503 is an orally active anxiolytic cyclopyrrolone derivative with low sedative potential. RP-60503 binds to the gamma-aminobutyric acidA (GABA)/benzodiazepine receptor with a Ki value of 1.16 nM. RP-60503 can be used for the research of neurological disease[1].
In Vivo:RP-60503 protects mice against pentylenetetrazole-induced seizures with ID50 values of 5.96 mg/kg[1].
RP-60503 (5 mg/kg, p.o.) shows anxiolytic effect in rats[1].
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