Xenin-8
CAS No. : 117442-28-1
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| Cat. No. : | HY-P1257 |
| M.Wt: | 1046.27 |
| Formula: | C51H79N15O9 |
| Purity: | >98 % |
| Solubility: | H2O |
Xenin-8, a C-terminal octapeptide, is a biologically active fragment of Xenin. Xenin is a 25-amino acid peptide of the neurotensin/xenopsin family. Xenin-8 stimulates basal insulin secretion and potentiates the insulin response to glucose in a dose-dependent manner (EC50=0.16 nM)[1]. In Vitro: Xenin-8 augments Arginine-induced insulin release (by 40%) and potentiates the glucagon responses to both Arginine (by 60%), Carbachol (by 50%). Xenin-8 counteracts the inhibition of glucagon release induced by increasing the glucose concentration[1].
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