Brodalumab
CAS No. : 1174395-19-7
(Synonyms: AMG 827; KHK4827)
| Size | Price | Stock |
|---|---|---|
| 1mg | $190 | In-stock |
| 5mg | $480 | In-stock |
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| Cat. No. : | HY-P9925 |
| M.Wt: | 1000.00 |
| Formula: | N/A |
| Purity: | >98 % |
| Solubility: | H2O |
Brodalumab (AMG 827) is a human anti-interleukin-17-receptor IgG2 monoclonal antibody that can be used for the research of moderate-to-severe plaque psoriasis and rheumatoid arthritis[1][2].
IC50 & Target:IL-17R[1]
In Vitro: Brodalumab (AMG 827) blocks the biological activity of IL-17A, IL-17F and IL17-A/F heterodimer signaling through the IL-17RA/RC complex, as well as IL-25 (IL-17E) signaling through the IL-17RA/RB complex[2].
Brodalumab is capable of inhibiting the inflammatory process in psoriasis[2].
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