PI3Kγ inhibitor 1
CAS No. : 1172118-03-4
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| Cat. No. : | HY-10549 |
| M.Wt: | 586.67 |
| Formula: | C32H26N8O2S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
PI3Kγ inhibitor 1 is a PI3Kδ and PI3Kγ inhibitor extracted from patent WO2014004470A1, Compound 168 in Table 4, has IC50s of <100 nM. IC50 & Target: IC50: <100 nM (PI3Kδ), <100 nM (PI3Kγ), <10 μM (PI3Kα), <10 μM (PI3Kβ)[1] In Vitro: In Table 3, PI3Kγ inhibitor 1 (Compound 168) inhibits PI3Kδ, PI3Kγ, PI3Kα and PI3Kβ with IC50s of <100 nM, <100 nM, <10 μM and <10 μM, respectively. PI3Kγ inhibitor 1 inhibits B cell proliferation with an EC50<100 nM.
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