Ricasetron
CAS No. : 117086-68-7
(Synonyms: BRL-46470)
| Size | Price | Stock |
|---|---|---|
| 5mg | $65 | In-stock |
| 10mg | $100 | In-stock |
| 25mg | $195 | In-stock |
| 50mg | $310 | In-stock |
| 100mg | $490 | In-stock |
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| Cat. No. : | HY-101709 |
| M.Wt: | 313.44 |
| Formula: | C19H27N3O |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
Ricasetron (BRL-46470) is a selective and orally active 5-HT3 receptor antagonist. Ricasetron displays little or no affinity for a variety of other neurotransmitter receptors. Ricasetron has anxiolytic and antiemetic effects[1][2]. In Vitro:In rat cerebral cortex/hippocampus, rat ileum, NG108-15 cell and HEK-5-HT3As cell homogenates, Ricasetron (BRL-46470) binds with high affinity (Kd (nM): 1.57, 2.49, 1.84 , 3.46, respectively)[1]. In Vivo:Ricasetron (10 μg/kg; drinking water; for 12-14 days) shows anxiolytic profile of behavioural effects in rats[2].
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