Quercetin (GMP)
CAS No. : 117-39-5
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| Cat. No. : | HY-18085G |
| M.Wt: | 302.24 |
| Formula: | C15H10O7 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Quercetin GMP is Quercetin (HY-18085) produced by using GMP guidelines. GMP small molecules works appropriately as an auxiliary reagent for cell therapy manufacture. Quercetin is a flavonoid antioxidant, a PI3K inhibitor and a SIRT1 Activator[1][2][3][4][5][6]. In Vitro:Quercetin GMP (10, 50 and 100 μM) increases osteogenesis of mesenchymal stem cells (mASCs)[1]. Quercetin GMP (0.1-10 μM) dose-dependently decreases osteoclastogenesis induced by RANKL[2]. Quercetin GMP (2 μM) dose-dependently enhances the osteogenic differentiation and angiogenic factor secretion of rat bone marrow-derived mesenchymal stem cells (rBMSCs)[3]. Quercetin GMP (2-5 μM) inhibits bone resorption via inhibiting the differentiation and activation of osteoclasts[4]. Quercetin (5 μM; 2-4 d) dose-dependently increases osteogenic differentiation[5]. Quercetin (0-5 μM; 6 d) incresese osteoblastic differentiation and extracellular matrix production and mineralization[6].
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