G-479


CAS No. : 1168092-22-5

1168092-22-5
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Cat. No. : HY-120454
M.Wt: 487.22
Formula: C16H15FIN5O4
Purity: >98 %
Solubility:
Introduction of 1168092-22-5 :

G-479 is the inhibitor for MEK and hERG channel (IC50=14 μM). G-479 inhibits the proliferation of HCT-116 and A375 with IC50 of 0.049 μM and 0.004 μM. G-479 exhibits good metabolic stability in liver microsomes and good pharmacokinetic characteristics in rats[1].

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