N6-[(2-Azidoethoxy)carbonyl]-L-lysine
CAS No. : 1167421-25-1
(Synonyms: UAA crosslinker 1)
| Size | Price | Stock |
|---|---|---|
| 5mg | $69 | In-stock |
| 10mg | $110 | In-stock |
| 25mg | $220 | In-stock |
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| Cat. No. : | HY-111434 |
| M.Wt: | 259.26 |
| Formula: | C9H17N5O4 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic;warming;heat to 60°C) |
UAA crosslinker 1 hydrochloride is an amber codon used for non-canonical amino acids (ncAAs) incorporation. The ncAAs can be incorporated into proteins in vivo by making use of the promiscuous activity of certain wildtype and engineered aminoacyl-tRNA synthetases[1]. UAA crosslinker 1 is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups.
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- N6-[(2-Azidoethoxy)carbonyl]-L-lysine
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