21-Hydroxypregnenolone
CAS No. : 1164-98-3
| Size | Price | Stock |
|---|---|---|
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| 10mg | $80 | In-stock |
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| Cat. No. : | HY-113020 |
| M.Wt: | 332.48 |
| Formula: | C21H32O3 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 25 mg/mL |
21-Hydroxypregnenolone is a CYP17 inhibitor. 21-Hydroxypregnenolone competitively inhibits CYP17-mediated 17α-hydroxylation activity of progesterone, with a Ki value of 36.4 μM[1]. In Vitro:21-Hydroxypregnenolone (20-100 μM; 10 min) competitively inhibits progesterone 17α-hydroxylation by recombinant human CYP17 expressed in E. coli membrane fractions with a Ki value of 36.4 μM, causing 81% inhibition at 100 μM[1].
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