SB-206606
CAS No. : 116049-78-6
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| Cat. No. : | HY-117239 |
| M.Wt: | 363.84 |
| Formula: | C19H22ClNO4 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
SB-206606, a stereoisomer of BRL 37344, is a potentially specific, beta 3-adrenergic receptor (β3-AR) ligand. The affinity of [3H]SB 206606 is 76 times higher for the β3-AR than for the beta 1/beta 2-adrenergic receptors[1].
In Vitro: [3H]SB-206606 binding to membranes from Chinese hamster ovary K1 cells transfected with the rat β3-AR with a Kd value of 58 nM[1].
[3H]SB-206606 binding to brown adipose tissue where beta 1-, beta 2-, and beta 3-adrenergic receptor subtypes are known to coexist with a Kd value of 38 nM[1].
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