Gardiquimod (diTFA)
CAS No. : 1159840-61-5
| Size | Price | Stock |
|---|---|---|
| 5mg | $50 | In-stock |
| 10mg | $80 | In-stock |
| 25mg | $180 | In-stock |
| 50mg | $280 | In-stock |
| 100mg | $480 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-103697A |
| M.Wt: | 541.44 |
| Formula: | C21H25F6N5O5 |
| Purity: | >98 % |
| Solubility: | H2O : 25 mg/mL (ultrasonic);DMSO : 50 mg/mL (ultrasonic) |
Gardiquimod diTFA, an imidazoquinoline analog, is a TLR7/8 agonist. Gardiquimod diTFA could inhibit HIV-1 infection of macrophages and activated peripheral blood mononuclear cells (PBMCs). Gardiquimod diTFA specifically activates TLR7 when used at concentrations below 10 μM[1][2]. IC50 & Target: TLR7, HIV-1 reverse transcriptase[1] In Vitro: Gardiquimod diTFA (6-60 μM ) significantly inhibits cDNA synthesis by HIV-1 reverse transcriptase[1]. In Vivo: Dendritic cells (DCs) in combination with Gardiquimod (1 mg/kg per mouse; i.p.; daily for 7 days) improves the anti-tumor effects of NK cells[2].
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- Gardiquimod (diTFA)
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