D159687
CAS No. : 1155877-97-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $55 | In-stock |
| 10mg | $88 | In-stock |
| 25mg | $177 | In-stock |
| 50mg | $266 | In-stock |
| 100mg | $400 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-15444 |
| M.Wt: | 366.84 |
| Formula: | C21H19ClN2O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 150 mg/mL (ultrasonic) |
D159687 is a selective PDE4D inhibitor[1].
IC50 & Target: PDE4D[1]
In Vitro: D159687 (1 μM, 0-24?hours) induces a transient increase in CREB phosphorylation which peaked at 6?hours after treatment[1].
D159687 (0.01-1 μM, 6 hours) causes optimal CREB phosphorylation at 1?μM[1].
In Vivo: D159687 (0.05-5 mg/kg; oral daily for a week) shows a potential recruitment or enhancement of synaptic function with increased task difficulty in female Cynomolgus macaques[2].
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