Calmodulin-Dependent Protein Kinase II (290-309)
CAS No. : 115044-69-4
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| Cat. No. : | HY-P1479 |
| M.Wt: | 2273.83 |
| Formula: | C103H185N31O24S |
| Purity: | >98 % |
| Solubility: | 10 mM in H2O |
Calmodulin-Dependent Protein Kinase II (290-309) is a potent CaMK antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase II[1]. IC50 & Target: IC50: 52 nM (calmodulin-dependent protein kinase II)[1] In Vitro: Peptide 290 to 309 is found to be a potent calmodulin antagonist with an IC50 of 52 nM for inhibition of Ca2+/calmodulin-dependent protein kinase. Neither truncation from the amino terminus (peptide 296-309) nor extension in the carboxyl-terminal direction (peptide 294-319) markedly affects calmodulin binding, whereas shortening the peptide from the carboxyl terminus (peptide 290-302) or from both ends (peptide 295-304) results in the elimination of this activity[1].
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