Azaserine
CAS No. : 115-02-6
(Synonyms: CI-337; O-Diazoacetyl-L-serine; P-165)
| Size | Price | Stock |
|---|---|---|
| 10mg | $150 | In-stock |
| 50mg | $395 | In-stock |
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| Cat. No. : | HY-B0919 |
| M.Wt: | 173.13 |
| Formula: | C5H7N3O4 |
| Purity: | >98 % |
| Solubility: | H2O : 50 mg/mL (ultrasonic) |
Azazerine (CI-337) is a competitive inhibitor of glutamine amidotransferase. Azaserine is an antibiotic, it shows antibacterial activities. Azazerine shows anti-tumor activities and it may also act as a tumor inducer. Azazerine can be used for the research of cancer and infection[1][2][3][4][5]. In Vitro:Azaserine (100 μg/mL; 6 h) causes some specific types of morphological changes of the sensitive organisms such as the characteristic elongation of Candida albicans cells[2]. Azaserine (0-10 μM) inhibits the growth of E. coli strains with MIC values of 12.11, 51.9, 69.2 and 69.2 μg/mL for UTH 4, UTH 7036, UTH 7048 and UTH 7049[3]. In Vivo:Azaserine (5 mg/kg; i.p. once or twice a week for 6 months) induces tumor in rats[1].
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