JNJ-28312141 (hydrochloride)
CAS No. : 1149939-55-8
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| Cat. No. : | HY-13496A |
| M.Wt: | 497.03 |
| Formula: | C26H33ClN6O2 |
| Purity: | >98 % |
| Solubility: |
JNJ-28312141 hydrochloride is an inhibitor for colony-stimulating factor-1 receptor (CSF-1R or FMS), with an IC50 of 0.69 nM. JNJ-28312141 hydrochloride inhibits proliferation of BDBM, MV-4-11, M-o7e, TF-1 with an IC50s of 2.6, 21, 41 and 150 nM, respectively. JNJ-28312141 hydrochloride exhibits anti-inflammatory activity in mouse arthritis model[1]. IC50 & Target:IC50: 0.69 nM (CSF-1R or FMS)[1]
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