PF-462991
CAS No. : 1149727-90-1
(Synonyms: PF-991)
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| Cat. No. : | HY-14433 |
| M.Wt: | 419.53 |
| Formula: | C25H29N3O3 |
| Purity: | >98 % |
| Solubility: |
PF-462991 (PF-991) is a S1P1 receptor agonist with an EC50 of 1.9 nM. PF-462991 functionally activates this receptor via the β-arrestin pathway. PF-462991 is applicable to research related to rheumatoid arthritis[1][2]. In Vitro:PF-462991 potently activates the S1P1 receptor with an EC50 of 1.9 nM; in β-arrestin functional assays, its selectivity for the S1P1 receptor is over 5263-fold higher than that for the S1P3 receptor[1].
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