Tripolin A
CAS No. : 1148118-92-6
(Synonyms: (E)-Tripolin A)
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| Cat. No. : | HY-124330 |
| M.Wt: | 253.25 |
| Formula: | C15H11NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Tripolin A ((E)-Tripolin A) is a specific non-ATP competitive Aurora A kinase inhibitor, with IC50 values of 1.5 μM and 7 μM for Aurora A and Aurora B, respectively[1].
IC50 & Target: IC50: 1.5 μM (Aurora A), 7 μM (Aurora A)[1].
In Vitro: Tripolin A induces mitotic spindle defects and spindle pole abnormalities[1].
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