SCH 2047069


CAS No. : 1146209-50-8

(Synonyms: MK-8267)

1146209-50-8
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Cat. No. : HY-122130
M.Wt: 439.43
Formula: C20H17F4N3O2S
Purity: >98 %
Solubility:
Introduction of 1146209-50-8 :

SCH 2047069 (MK-8267) is an orally active kinesin spindle protein (KSP) inhibitor (Kd: 0.5 nM) that can cross the blood-brain barrier. SCH 2047069 exhibits an IC50 value of ≤ 5 nM against the KSP ATPase. SCH 2047069 exhibits broad-spectrum antitumor activity. SCH 2047069 can induce mitotic arrest and apoptosis in tumor cells. SCH 2047069 can be used in the research of tumors such as ovarian cancer, colon cancer, glioblastoma, and lymphoma[1][2].

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