Olopatadine
CAS No. : 113806-05-6
| Size | Price | Stock |
|---|---|---|
| 5mg | $160 | In-stock |
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| Cat. No. : | HY-W062109 |
| M.Wt: | 337.41 |
| Formula: | C21H23NO3 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
Olopatadine is an orally active and selective histamine 1 (H1) receptor antagonist and a mast cell stabilizer. Olopatadine prevents immunologically stimulated pro-inflammatory mediator release from human conjunctival mast cells. Olopatadine can be used for researching allergic conjunctivitis[1][2]. In Vitro: Olopatadine inhibits anti-IgE antibody-mediated release of TNF-α from human conjunctival mast cells, and significantly decreases the mast cell supernatant-mediated upregulation of ICAM (intercellular adhesion molecule)-1 on human conjunctival epithelial cells in vitro[2].
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