Biotin-VAD-FMK


CAS No. : 1135688-15-1

1135688-15-1
Price and Availability of CAS No. : 1135688-15-1
Size Price Stock
1mg $290 In-stock
5mg $580 In-stock
10mg $950 In-stock
25mg $1900 In-stock
50mg $3050 In-stock
100mg $4900 In-stock
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Cat. No. : HY-100894
M.Wt: 672.81
Formula: C30H49FN6O8S
Purity: >98 %
Solubility: DMSO : ≥ 27.3 mg/mL
Introduction of 1135688-15-1 :

Biotin-VAD-FMK is a cell permeable, irreversible biotin-labeled caspase inhibitor, used to identify active caspases in cell lysates. In Vitro: Biotin-VAD-FMK is a synthetic peptide designed as a methyl ester to facilitate cell permeability. In Vivo: To examine whether caspase-2 is activated in the absence of proteolytic cleavage, an in vivo affinity labeling approach is used, using the biotinylated caspase inhibitor biotin-VAD-fmk that detects only active caspases[2].

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