VU0357017


CAS No. : 1135681-23-0

(Synonyms: CID-25010775 (free base))

1135681-23-0
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Cat. No. : HY-19752
M.Wt: 333.43
Formula: C18H27N3O3
Purity: >98 %
Solubility:
Introduction of 1135681-23-0 :

VU0357017 (CID-25010775) is a potent, selective and brain-penetrant allosteric agonist of M1 muscarinic acetylcholine receptor, with an EC50 of 477 nM. VU0357017 is highly selective for M1 and has no activity at M2-M5 up to the highest concentrations tested (30 μM). VU0357017 can be used for the research of Alzheimer’s disease and schizophrenia[1][2][3].

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