ALW-II-49-7
CAS No. : 1135219-23-6
| Size | Price | Stock |
|---|---|---|
| 1mg | $82 | In-stock |
| 5mg | $206 | In-stock |
| 10mg | $310 | In-stock |
| 25mg | $560 | In-stock |
| 50mg | $850 | In-stock |
| 100mg | $1280 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
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| Cat. No. : | HY-18833 |
| M.Wt: | 414.38 |
| Formula: | C21H17F3N4O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
ALW-II-49-7 is a selective EphB2 kinase inhibitor with an EC50 value of 40 nM in cell[1].
IC50 & Target:EphB2[1]
In Vitro: ALW-II-49-7 (compound 9) exhibits selectivity profile of binding to a set of kinases including b-raf, CSF1R, DDR1, DDR2, EphA2, EphA5, EphA8, EphB1, EphB2, EphB3, Frk, Kit, Lck, p38a, p38b, PDGFRa, PDGFRb, and Raf1[1].
ALW-II-49-7 (0.01-10 μM; 1 h) inhibits EphB2 tyrosine kinase activity in U87 glioblastoma cells. EphB2 is added in media at 2 μg/mL[1].
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