ABT-072


CAS No. : 1132936-00-5

1132936-00-5
Price and Availability of CAS No. : 1132936-00-5
Size Price Stock
1mg $250 In-stock
5mg $500 In-stock
10mg $800 In-stock
25mg $1750 In-stock
50mg $2800 In-stock
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200 mg Get quote
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Cat. No. : HY-101634
M.Wt: 469.55
Formula: C24H27N3O5S
Purity: >98 %
Solubility: DMSO : 80 mg/mL (ultrasonic)
Introduction of 1132936-00-5 :

ABT-072 is an orally active and potent non-nucleoside HCV NS5B polymerase inhibitor (HCV GT1a EC50=1 nM; HCV GT1b EC50=0.3 nM)[1][2][3]. IC50 & Target: NS5B polymerase[1] In Vitro: ABT-072 is a non-nucleoside NS5B polymerase inhibitor with nanomolar potency in vitro against genotype 1a and 1b hepatitis C virus polymerases[1]. In Vivo: ABT-072 (5 and/or 30 mg/kg; i.v. or p.o.) shows good PK properties[3].
ABT-072 (2.5 and/or 30 mg/kg; i.v. or p.o.) shows low plasma clearance and high oral bioavailability[3].

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