Robotnikinin
CAS No. : 1132653-79-2
| Size | Price | Stock |
|---|---|---|
| 1mg | $340 | In-stock |
| 5mg | $850 | In-stock |
| 10mg | $1360 | In-stock |
| 25mg | $2320 | In-stock |
| 50 mg | Get quote | |
| 100 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-100515 |
| M.Wt: | 454.95 |
| Formula: | C25H27ClN2O4 |
| Purity: | >98 % |
| Solubility: | DMSO : 20 mg/mL (ultrasonic;warming) |
Robotnikinin is a small molecule capable of binding to and inhibiting the activity of Sonic Hedgehog (Shh) signaling up stream of Smo[1][2].
In Vitro: Robotnikinin demonstrates ShhN-binding capacity at concentrations between 1.56 μM and 25 μM, with a KD of 3.1 μM derived from kinetic data[2].
Robotnikinin (50 µM) prevents the ShhN-induced LC3-II increase[3].
Robotnikinin (5 μM) downregulates classical NF-κB pathway proteins in H929 and U266 cell lines cocultured with HS-5 cells, suggesting a link between Hh signaling and the NF-κB pathway in MM[4].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- Robotnikinin
- Cat. No.:
- HY-100515
- Quantity:
Your information is safe with us.