Benzquinamide (hydrochloride)
CAS No. : 113-69-9
(Synonyms: P2647 (hydrochloride); BZQ (hydrochloride); Benzoquinamide (hydrochloride))
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| Cat. No. : | HY-U00244A |
| M.Wt: | 440.96 |
| Formula: | C22H33ClN2O5 |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO;10 mM in DMSO |
Benzquinamide (P2647) is an antiemetic which can bind to the α2A, α2B, and α2C adrenergic receptors (α2-AR) with Ki values of 1,365, 691, and 545 nM, respectively. Benzquinamide also inhibits P-glycoprotein mediated drug efflux and potentiates anticancer agent cytotoxicity in multidrug resistant cells[1][2]. IC50 & Target:Ki: 1,365, 691, and 545 nM (α2A, α2B,α2C receptor)[1]
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