IM-12
CAS No. : 1129669-05-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $61 | In-stock |
| 10mg | $98 | In-stock |
| 25mg | $196 | In-stock |
| 50mg | $300 | In-stock |
| 100mg | $450 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-12292 |
| M.Wt: | 377.41 |
| Formula: | C22H20FN3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : ≥ 54.9 mg/mL |
IM-12 is an inhibitor of GSK-3β, with an IC50 of 53 nM, and also enhances Wnt signalling. IC50 & Target: IC50: 53 nM (GSK-3β)[1] In Vitro: IM-12 inhibits GSK-3β in ReNcell VM cells, with I50 of 3.8 μM. IM-12 (3 μM) enhances the β-catenin amount, with no further effect at lower or higher concentration. IM-12 (3 μM) also attenuates the proliferation of ReNCell VM cells. IM-12 increases TCF-activity of ReNcell VM[1].
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