AG311
CAS No. : 1126602-42-3
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-116107 |
| M.Wt: | 321.40 |
| Formula: | C17H15N5S |
| Purity: | >98 % |
| Solubility: | 10 mM in DMSO |
AG311 is an anticancer and antimetastatic agent. AG311 induces rapid necrosis in numerous cancer cell lines[1].
In Vitro:AG311 (0-30 μM; 48 h) shows cytotoxicity against cancer cells[1].
AG311 (10-40 μM; 0-150 min) selectively induces membrane permeabilization in breast cancer cells (compared to HUVECs)[1].
AG311 (25 μM; 20 min) induces necrosis and lacks molecular markers of apoptosis in MDA-MB-435 cells[1].
AG311 (15-25 μM) affects calcium homeostasis and induces plasma membrane depolarization in MDA-MB-435 cells[1].
AG311 (5-20 μM) induces rapid mitochondrial membrane changes and mitochondrial dysfunction in MDA-MB-435 cells[1].
AG311 (0-14 μM; 30 h) inhibits breast cancer cell migration[1].
In Vivo:AG311 (23 mM; intratumoral; once daily for 2 days) increases necrosis in mice[1].
AG311 (45 mg/kg; i.p.; twice weekly for 30 days) inhibits tumor growth and lung metastases in mice[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- AG311
- Cat. No.:
- HY-116107
- Quantity:
Your information is safe with us.