| Size | Price | Stock |
|---|---|---|
| 5mg | $98 | In-stock |
| 10mg | $156 | In-stock |
| 25mg | $313 | In-stock |
| 50mg | $496 | In-stock |
| 100mg | $795 | In-stock |
| 200 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
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| Cat. No. : | HY-121966 |
| M.Wt: | 287.31 |
| Formula: | C16H17NO4 |
| Purity: | >98 % |
| Solubility: | DMSO : 100 mg/mL (ultrasonic) |
Riparin is a nonspecific smooth muscle relaxant. Riparin exerts spasmolytic effect by inhibiting Ca2+ influx and inhibiting the release of intracellular calcium ion stores[1].
In Vitro:In rat depolarized uterus, Riparin inhibits in a reversible and noncompetitive manner CaCl2-induced contraction, a response mediated through voltage-dependent Ca2+ channels. The pD2 value for Riparin is 4.98. Riparin is ineffective in suppressing noradrenaline-induced sustained contractions of rabbit aortic strips[1].
In the aorta, Riparin (IC50 of 10.1 μM) inhibits intracellular calcium-dependent transient contractions[1].
In guinea-pig alveolar leucocytes, Riparin (IC50 3.2 μM) inhibits intracellular Ca2+ accumulation induced by the calcium ionophore A23187[1].
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