BRL 52537 (hydrochloride)
CAS No. : 112282-24-3
| Size | Price | Stock |
|---|---|---|
| 5mg | $95 | In-stock |
| 10mg | $150 | In-stock |
| 25mg | $280 | In-stock |
| 50mg | $420 | In-stock |
| 100mg | $630 | In-stock |
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| 500 mg | Get quote | |
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| Cat. No. : | HY-101079 |
| M.Wt: | 391.76 |
| Formula: | C18H25Cl3N2O |
| Purity: | >98 % |
| Solubility: | DMSO : 5 mg/mL (ultrasonic;warming;heat to 60°C);Methanol : 25 mg/mL (ultrasonic) |
BRL 52537 hydrochloride is a highly selective κ-Opioid receptor (KOR) agonist with Kis of 0.24 nM and 1560 nM for κ and μ subtypes, respectively. BRL 52537 hydrochloride decreases ischemia-evoked NO production as a potential mechanism of neuroprotection. BRL 52537 hydrochloride attenuates early stroke damage[1]. IC50 & Target:Ki: 0.24 nM (κ-Opioid receptor) and 1560 nM (μ-Opioid receptor)[1]
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