Pam3CSK4
CAS No. : 112208-00-1
(Synonyms: Pam3Cys-Ser-(Lys)4)
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| Cat. No. : | HY-P1180 |
| M.Wt: | 1510.23 |
| Formula: | C81H156N10O13S |
| Purity: | >98 % |
| Solubility: | H2O |
Pam3CSK4 is a toll-like receptor 1/2 (TLR1/2) agonist with an EC50 of 0.47 ng/mL for human TLR1/2[1].
In Vitro: Pam3CSK4 is a TLR1/2 heterodimer recognises triacylated lipopeptides[1].
Pam3CSK4 (1 μg/mL) enhances the antibacterial functions of granulocyte macrophage-colony stimulating factor (GM-CSF) induced neutrophils to Methicillin-resistant Staphylococcus aureus[2].
In Vivo: Pam3CSK4 (5 mg/kg; i.p.; once a day for 9 days) alters brain, spleen and liver weights in neonatal mice[3].
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