U-75875
CAS No. : 112190-24-6
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| Cat. No. : | HY-105448 |
| M.Wt: | 812.01 |
| Formula: | C45H61N7O7 |
| Purity: | >98 % |
| Solubility: |
U-75875 is a HIV-1 protease inhibitor. U-75875 can block Gag-Pol protein processing and viral maturation and replication. U-75875 can be used for the research of infection[1][2].
In Vitro:U-75875 shows an IC50 of 100 μM to SIV-infected PBMC cultures[1].
U-75875 (0.1 μM, 2 h) reduces HIV-1 p24 Ag levels in human fetal brain cells[1].
In Vivo:U-75875 (7-20 mg/kg, i.v., daily for 26 days) decreases virus load in Rhesus monkeys infected with SIV Delta B670[1].
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