NecroX-2
CAS No. : 1120333-38-1
| Size | Price | Stock |
|---|---|---|
| 100 mg | Get quote | |
| 250 mg | Get quote | |
| 500 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-179037 |
| M.Wt: | 516.68 |
| Formula: | C25H32N4O4S2 |
| Purity: | >98 % |
| Solubility: |
NecroX-2 is a potent inhibitor of caspase-independent necrosis. NecroX-2 exhibits antioxidant activity by scavenging DPPH radicals and peroxynitrite. NecroX-2 inhibits t-BHP-induced mitochondrial ROS/RNS generation, and protects t-BHP and Doxorubicin (HY-15142A)-induced cell death in vitro. NecroX-2 can be used for research on neurological diseases[1][2].
In Vitro:NecroX-2 displays in vitro antioxidant activity with an IC50 of 17 μM in the DPPH radical-scavenging assay, and exhibits in vitro peroxynitrite scavenging activity with an IC50 of 0.9 μM[1].
NecroX-2 (0.4-10 μM; 2 h) inhibits copper ion-induced LDL oxidation[1].
NecroX-2 (2 h) potently inhibits t-BHP-induced mitochondrial ROS/RNS generation in H9C2 cells with an IC25 < 0.1 μM[1].
NecroX-2 (0.1-10 μM; 30 min pretreat) provides dose-dependent cytoprotection against t-BHP-induced cell death in H9C2 cells[1].
NecroX-2 (0.063-1.0 μM; 30 min pretreat) protects primary rat hepatocytes from Doxorubicin-induced cell death in a dose-dependent manner, with an IC50 of 0.12 μM [1].
NecroX-2 (0.3 μM; 30 min) suppresses caspase-independent necrosis in Cd-exposed SH-SY5Y and PC12 neuronal cells[2].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- NecroX-2
- Cat. No.:
- HY-179037
- Quantity:
Your information is safe with us.