Trimethyloctadecylammonium (bromide)


CAS No. : 1120-02-1

1120-02-1
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Cat. No. : HY-W013158
M.Wt: 392.51
Formula: C21H46BrN
Purity: >98 %
Solubility: DMSO : 10 mg/mL (ultrasonic)
Introduction of 1120-02-1 :

Trimethyloctadecylammonium bromide is an inhibitor of dynamin, with an IC50 value of 1.9 μM for dynamin I. Trimethyloctadecylammonium bromide exhibits antibacterial activity against Staphylococcus aureus[1][2]. IC50 & Target:IC50: 1.9 μM (Dynamin I)[1] In Vitro:Trimethyloctadecylammonium bromide (1 μM-100 μM; 10 min) inhibits EGF-A488 endocytosis in COS-7 cells, with an IC50 value of 16 μM[1].
Trimethyloctadecylammonium bromide (30 μM; 10 min; 37 ℃) shows no effect on EGFR activation in A431 cells with insignificant EGFR autophosphorylation change[1].
Trimethyloctadecylammonium bromide (stearyl-) (1 nM-1 mM) inhibits Staphylococcus aureus with of 59.5 nM (CKD assay) and 0.33 mM (CMC assay), respectively[2].

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