1-Hydroxyoctadecane


CAS No. : 112-92-5

(Synonyms: Stearyl alcohol)

112-92-5
Price and Availability of CAS No. : 112-92-5
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500g $27 In-stock
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Cat. No. : HY-Y1809
M.Wt: 270.49
Formula: C18H38O
Purity: >98 %
Solubility: DMSO : 5 mg/mL (ultrasonic)
Introduction of 112-92-5 :

1-Hydroxyoctadecane (Stearyl alcohol) is a long-chain fatty alcohol and excipient. 1-Hydroxyoctadecane forms a closed oil film, thereby reducing transepidermal water loss (TEWL) and promoting skin moisturization. 1-Hydroxyoctadecane improves Imiquimod (HY-B0180)-induced psoriatic skin inflammation in mice[1]. In Vivo:1-Hydroxyoctadecane (1%-20% in Vaseline; topical application on the back of mice; daily) dose-dependently ameliorates Imiquimod (HY-B0180)-induced psoriasis-like skin inflammation in mice, including reducing PASI scores, inhibiting epidermal thickening, and decreasing the number of Ki67+ and PCNA+ cells (keratinocyte proliferation markers)[1].

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