Vitamin U (chloride)


CAS No. : 1115-84-0

(Synonyms: S-Methylmethionine sulfonium (chloride))

1115-84-0
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Cat. No. : HY-N2551
M.Wt: 199.70
Formula: C6H14ClNO2S
Purity: >98 %
Solubility: H2O : 100 mg/mL (ultrasonic)
Introduction of 1115-84-0 :

Vitamin U (S-Methylmethionine sulfonium) chloride is an orally active anti-ulcer agent with antioxidant activity. Vitamin U inhibits adipocyte differentiation. Vitamin U promotes skin wound healing.Vitamin U can be used in the research of gastrointestinal ulceration[1][2][3][4][5]. In Vitro:Vitamin U chloride (100 μM, 24 h) promotes the growth and migration of human dermal fibroblasts(hDFs)[1].
Vitamin U chloride (0-1 mM, 24 h) activates ERK1/2 in hDFs[1].
Vitamin U chloride (0.1 g/L in the nutrient solution) reduces cell membrane damage in higher plants exposed to low-temperature stress[2].
Vitamin U chloride (10-100 mM, 7 days) inhibits adipocyte differentiation via down-regulation of adipogenic factors and up-regulation of AMPK activity[3].
In Vivo:Vitamin U chloride (50 mg/kg, oral gavage) prevents valproic acid-induced liver injury in rats[4].
Vitamin U chloride (50 mg/kg, oral gavage for 3 days) shows antioxidant effect and prevents GalN-induced gastric damage in rats[5].

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