Ceronapril


CAS No. : 111223-26-8

(Synonyms: Ceranapril; SQ 29852)

111223-26-8
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Cat. No. : HY-106816
M.Wt: 440.47
Formula: C21H33N2O6P
Purity: >98 %
Solubility: 10 mM in DMSO
Introduction of 111223-26-8 :

Ceronapril (SQ 29852) is a potent and orally active angiotensin converting enzyme (ACE) inhibitor with an IC50 of 36 nM[1]. IC50 & Target:IC50: 36 nM (ACE)[1] In Vivo:Ceronapril (SQ 29852) inhibits ACE in male SD rats with ED50s of 0.063 μM/kg and 0.53 μM/kg by IV and PO, respectively[1].
Ceronapril (100 mg/kg; p.o.; single dose or twice daily for 3 days) blocks ACE in peripheral sites in rats[2].

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