CGS 20625
CAS No. : 111205-55-1
| Size | Price | Stock |
|---|---|---|
| 5mg | $125 | In-stock |
| 10mg | $200 | In-stock |
| 25mg | $400 | In-stock |
| 50mg | $640 | In-stock |
| 100 mg | Get quote | |
| 200 mg | Get quote | |
| We match the lowest price on market. | ||
We offer a substantial discount on larger orders, please inquire via [email protected]
or Fax: (86)21-58955996
Inquiry for price and availability only. Please place your order via our email or fax.
| Cat. No. : | HY-106316 |
| M.Wt: | 309.36 |
| Formula: | C18H19N3O2 |
| Purity: | >98 % |
| Solubility: | DMSO : 50 mg/mL (ultrasonic;warming;heat to 60°C) |
CGS 20625 is a potent, selective and orally active partial agonist for the central benzodiazepine receptor. CGS 20625 inhibits [3H]-flunitrazepam binding to central benzodiazepine receptors with an IC50 of 1.3 nM. CGS 20625 enhances GABA in Xenopus laevis oocytes . CGS 20625 can be used for the research of pentylenetetrazol-induced seizures and anxiety[1][2].
IC50 & Target:IC50: 1.3 nM ([3H]-flunitrazepam binding to central benzodiazepine receptors)[1]
In Vitro:CGS 20625 (0.01-100 μM) significantly enhances GABA-induced chloride currents in Xenopus laevis oocytes expressing α1β2γ1 GABAA receptors[2].
CGS 20625 (0.01-100 μM) maximally enhances GABA in Xenopus laevis oocytes expressing α1β2γ2S GABAA receptors with an EC50 of 11.2 μM[2].
CGS 20625 (0.01-100 μM) enhances GABA in Xenopus laevis oocytes expressing α1β2 GABAA receptors, with an EC50[2].
In Vivo:CGS 20625 (p.o.) shows efficacy in preventing pentylenetetrazol-induced seizures (ED50 = 0.7 mg/kg)[1].
Lorem ipsum dolor sit amet, consectetur adipisicing elit. Autem earum hic iste maiores, nam neque rem suscipit. Adipisci consequatur error exercitationem fugit ipsam optio qui, quibusdam repellendus sed vero! Debitis.
Inquiry Information- Product Name:
- CGS 20625
- Cat. No.:
- HY-106316
- Quantity:
Your information is safe with us.